Source assertion

PDBe/SIFTS maps PDB 5C8I to UniProt P00918 with chain-level identity and coverage retained.

Evidence ID: STRUCTURE:PDB:5C8I:UNIPROT:P00918
Subject dossier: ca2
Source chain: uniprot + pdbe
Upstream record: 5C8I
Corpus snapshot: 2026-07-14T09:23:31Z
Admission status: Admitted release record

Experimental structure

Joint X-ray/neutron structure of Human Carbonic Anhydrase II in complex with Methazolamide

PDB ID: 5C8I
Experimental method: Neutron Diffraction, X-ray diffraction
Resolution: %!f(*float64=0xc000068e88) Å
SIFTS identifier: CAH2_HUMAN
Deposited: 20150625
Released / revised: 20160720 / 20251112

Chain-level mapping

Entity	Chain	Structural asym	Identity	Coverage	UniProt range
1	`A`	`A`	100.0%	100.0%	1–260

Experimental constructs

Entity	Chains / asym IDs	Molecule	Length	Mutation flag	Preparation
1	A / A	Carbonic anhydrase 2polypeptide(L)	260 residues	not reported in admitted source fields	Genetically manipulated

Interpretation boundary

This record represents an experimentally determined structure, not a predicted model. A co-crystal ligand, if present upstream, does not by itself establish affinity. This record does not infer kinetics, pathway rate, or metabolic flux.

Snapshot provenance

Each retained corpus build input is identified by retrieval time, snapshot path, SHA-256 digest, and exact upstream request. The snapshot files are not embedded in the served binary; the provenance identifiers remain dependencies of this one admitted record, not interchangeable citations.

Retrieved	Snapshot	SHA-256	Upstream request
2026-07-14T09:21:31Z	`raw/uniprot/entries/P00918.json`	`ed44906dd1b976f4c8b0399e9e3a7a4af09b673c035a201e218a4880821c1179`	Open exact source
2026-07-14T09:21:41Z	`raw/pdbe/mappings/5c8i.json`	`e97e60a9b2f2535266109630518d7ec7b8e0043495de4a2e76d198b92dbf152f`	Open exact source
2026-07-14T09:22:16Z	`raw/pdbe/summary/chunk-03.json`	`d318ed911ff2a8e3f25986a39c37baa2a3bb13c1d2a75d036924ca34ffa2b9cb`	Open exact source
2026-07-14T09:22:16Z	`raw/pdbe/experiment/chunk-03.json`	`8bbfae15de944b1cacdf21ee7a42caf9f09149a49b6fdf48f69df854b06973c9`	Open exact source
2026-07-14T09:22:17Z	`raw/pdbe/molecules/chunk-03.json`	`e94951408bdc68a6d0767211c754ae03dc74c4cf253ad3a7626c02d4aaba5eeb`	Open exact source