Source assertion

PDBe/SIFTS maps PDB 5E2M to UniProt P00915 with chain-level identity and coverage retained.

Evidence ID: STRUCTURE:PDB:5E2M:UNIPROT:P00915
Subject dossier: ca1
Source chain: uniprot + pdbe
Upstream record: 5E2M
Corpus snapshot: 2026-07-14T09:23:31Z
Admission status: Admitted release record

Experimental structure

Crystal structure of human carbonic anhydrase isozyme I with 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide

PDB ID: 5E2M
Experimental method: X-ray diffraction
Resolution: %!f(*float64=0xc0000690a0) Å
SIFTS identifier: CAH1_HUMAN
Deposited: 20151001
Released / revised: 20161005 / 20240110

Chain-level mapping

Entity	Chain	Structural asym	Identity	Coverage	UniProt range
1	`A`	`A`	100.0%	99.2%	3–261
1	`B`	`B`	100.0%	99.2%	3–261

Experimental constructs

Entity	Chains / asym IDs	Molecule	Length	Mutation flag	Preparation
1	A, B / A, B	Carbonic anhydrase 1polypeptide(L)	260 residues	not reported in admitted source fields	Genetically manipulated

Interpretation boundary

This record represents an experimentally determined structure, not a predicted model. A co-crystal ligand, if present upstream, does not by itself establish affinity. This record does not infer kinetics, pathway rate, or metabolic flux.

Snapshot provenance

Each retained corpus build input is identified by retrieval time, snapshot path, SHA-256 digest, and exact upstream request. The snapshot files are not embedded in the served binary; the provenance identifiers remain dependencies of this one admitted record, not interchangeable citations.

Retrieved	Snapshot	SHA-256	Upstream request
2026-07-14T09:21:31Z	`raw/uniprot/entries/P00915.json`	`b3bde31c781c25e15bf68bd00c694f9b1027cdc49ec26688ca7d047de2a6ca95`	Open exact source
2026-07-14T09:21:35Z	`raw/pdbe/mappings/5e2m.json`	`7fe0789c8f51eefef6637c57b60a2ed7e0fcd3c60e36aa29302d08d587df3a4f`	Open exact source
2026-07-14T09:22:16Z	`raw/pdbe/summary/chunk-03.json`	`d318ed911ff2a8e3f25986a39c37baa2a3bb13c1d2a75d036924ca34ffa2b9cb`	Open exact source
2026-07-14T09:22:16Z	`raw/pdbe/experiment/chunk-03.json`	`8bbfae15de944b1cacdf21ee7a42caf9f09149a49b6fdf48f69df854b06973c9`	Open exact source
2026-07-14T09:22:17Z	`raw/pdbe/molecules/chunk-03.json`	`e94951408bdc68a6d0767211c754ae03dc74c4cf253ad3a7626c02d4aaba5eeb`	Open exact source