Source assertion
PDBe/SIFTS maps PDB 5KU6 to UniProt P22748 with chain-level identity and coverage retained.
Experimental structure
Crystal structure for the complex of human carbonic anhydrase IV and methazolamide
- PDB ID
5KU6- Experimental method
- X-ray diffraction
- Resolution
- %!f(*float64=0xc000069620) Å
- SIFTS identifier
CAH4_HUMAN- Deposited
- 20160712
- Released / revised
- 20170726 / 20241023
Chain-level mapping
| Entity | Chain | Structural asym | Identity | Coverage | UniProt range |
|---|---|---|---|---|---|
| 1 | A | A | 100.0% | 90.5% | 19–284 |
| 1 | B | B | 100.0% | 90.5% | 19–284 |
| 1 | C | C | 100.0% | 90.5% | 19–284 |
| 1 | D | D | 100.0% | 90.5% | 19–284 |
Experimental constructs
| Entity | Chains / asym IDs | Molecule | Length | Mutation flag | Preparation |
|---|---|---|---|---|---|
| 1 | A, B, C, D / A, B, C, D | Carbonic anhydrase 4polypeptide(L) | 266 residues | not reported in admitted source fields | Genetically manipulated |
Interpretation boundary
This record represents an experimentally determined structure, not a predicted model. A co-crystal ligand, if present upstream, does not by itself establish affinity. This record does not infer kinetics, pathway rate, or metabolic flux.
Snapshot provenance
Each retained corpus build input is identified by retrieval time, snapshot path, SHA-256 digest, and exact upstream request. The snapshot files are not embedded in the served binary; the provenance identifiers remain dependencies of this one admitted record, not interchangeable citations.
| Retrieved | Snapshot | SHA-256 | Upstream request |
|---|---|---|---|
| 2026-07-14T09:21:32Z | raw/uniprot/entries/P22748.json | 28fa76c5a216b9356479d42199f709dd46e662172f2872078a5491cfe2c618f1 | Open exact source |
| 2026-07-14T09:21:53Z | raw/pdbe/mappings/5ku6.json | 6a4807ddebf1fff22928ccad710da023c52adf2c5d9ca945ff6a0fc6a00d8df8 | Open exact source |
| 2026-07-14T09:22:16Z | raw/pdbe/summary/chunk-03.json | d318ed911ff2a8e3f25986a39c37baa2a3bb13c1d2a75d036924ca34ffa2b9cb | Open exact source |
| 2026-07-14T09:22:16Z | raw/pdbe/experiment/chunk-03.json | 8bbfae15de944b1cacdf21ee7a42caf9f09149a49b6fdf48f69df854b06973c9 | Open exact source |
| 2026-07-14T09:22:17Z | raw/pdbe/molecules/chunk-03.json | e94951408bdc68a6d0767211c754ae03dc74c4cf253ad3a7626c02d4aaba5eeb | Open exact source |