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Executable evidence boundary

Comparison laboratory

The server evaluates identity, endpoint, value, assay, condition, molecular-form, dependence, direction, evidence-class, and provenance rules. The interface cannot override a refusal.

Corpus records

Select two admitted measurements.

Authoritative decision

Comparison refused

Condition mismatch · The pH differs even though the other fixture fields match.

LEFT / fixture-condition-aP00918 · Ki

= 12 nM · biochemical · pH 7.4

RIGHT / fixture-condition-bP00918 · Ki

= 12 nM · biochemical · pH 6.5

CONDITION_MISMATCH

conditions

The recorded pH, temperature, substrate or buffer differs.

Needed: Use a matched protocol or keep the values side by side without ranking.
Policy principles

Refusal is a first-class result.

  1. Compare only exact, versioned protein identities; names are not identifiers.
  2. Rank quantitative measurements only within one assay or an independently reviewed matched-protocol group.
  3. Keep Ki, Kd, IC50, EC50, Km, kcat and kcat/Km as separate endpoint types.
  4. Preserve source relation operators and raw values; a bound is not a point estimate.
  5. Keep experimental constructs, variants, tested molecular forms and conditions explicit.
  6. Display a refusal with actionable reasons whenever strict comparison requirements are not met.
Download the machine-readable policy →