Release-checked dossier · independent review pending
UniProt-reviewed human alpha-carbonic-anhydrase scope record. Seven experimental structure mappings, two direct assay activities, and one reaction assignment remain tied to CA13 rather than backfilled from nearby paralogs. This release admits 10 source-linked records for this accession; selection counts are not complete upstream-database counts.
Normalized identity
- Gene
- CA13
- UniProt accession
Q8N1Q1- Catalytic status
- Catalytic
- Review state
- UniProt-reviewed
- Taxon
- 9606
- Entry version
- 181 · 2026-06-10
- Sequence identity
- v1 · CRC64
AE677F028ED729FE - Sequence length
- 262 residues
- Selected structures
- 7
- Selected activities
- 2
- Reaction assignments
- 1
- ChEMBL targets
- CHEMBL3912
UniProt identity snapshot provenance
Snapshot paths identify retained corpus build inputs; those source files are not embedded in the served binary. The release keeps the path, digest, retrieval time, and exact upstream request together.
| Retrieved | Build-input snapshot | SHA-256 | Upstream request |
|---|---|---|---|
| 2026-07-14T09:21:33Z | raw/uniprot/entries/Q8N1Q1.json | 606f7712a41abd05d3b9d0522bbefd377f44b400f37aba7cab2c788361ea41dd | Open exact source |
Source-reported location comments
- Cytoplasm, cytosol
UniProt function text
Catalyzes the reversible conversion of carbon dioxide to hydrogencarbonate/bicarbonate and thus is essential in the regulation of pH and metabolic processes
Admitted evidence
Assay activityCA13 · ChEMBL activity 29494582949458 · 1 refusal code(s)Assay activityCA13 · ChEMBL activity 33800393380039 · 1 refusal code(s)Experimental structureCA13 · PDB 3CZV3CZVExperimental structureCA13 · PDB 3D0N3D0NExperimental structureCA13 · PDB 3DA23DA2Experimental structureCA13 · PDB 4HU14HU1Experimental structureCA13 · PDB 4KNM4KNMExperimental structureCA13 · PDB 4KNN4KNNExperimental structureCA13 · PDB 5OGJ5OGJReaction assignmentCA13 · RHEA:10748 assignmentRHEA:10748