Release-checked dossier · independent review pending
UniProt-reviewed human alpha-carbonic-anhydrase scope record. Ectodomain constructs, full-length protein and cell-based contexts remain separate. This release admits 11 source-linked records for this accession; selection counts are not complete upstream-database counts.
Normalized identity
- Gene
- CA9
- UniProt accession
Q16790- Catalytic status
- Catalytic
- Review state
- UniProt-reviewed
- Taxon
- 9606
- Entry version
- 218 · 2026-06-10
- Sequence identity
- v2 · CRC64
BA67195483F0F5CE - Sequence length
- 459 residues
- Selected structures
- 8
- Selected activities
- 2
- Reaction assignments
- 1
- ChEMBL targets
- CHEMBL3594
UniProt identity snapshot provenance
Snapshot paths identify retained corpus build inputs; those source files are not embedded in the served binary. The release keeps the path, digest, retrieval time, and exact upstream request together.
| Retrieved | Build-input snapshot | SHA-256 | Upstream request |
|---|---|---|---|
| 2026-07-14T09:21:33Z | raw/uniprot/entries/Q16790.json | 77abc0523fc4c2b797ea15d860a4bb98365bcf0caec1ee88ba765973570f1f22 | Open exact source |
Source-reported location comments
- Nucleus
- Nucleus, nucleolus
- Cell membrane · Single-pass type I membrane protein
- Cell projection, microvillus membrane · Single-pass type I membrane protein
UniProt function text
Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions)
Admitted evidence
Assay activityCA9 · ChEMBL activity 23939672393967 · 1 refusal code(s)Assay activityCA9 · ChEMBL activity 25983282598328 · 1 refusal code(s)Experimental structureCA9 · PDB 2HKF2HKFExperimental structureCA9 · PDB 3IAI3IAIExperimental structureCA9 · PDB 5DVX5DVXExperimental structureCA9 · PDB 5FL45FL4Experimental structureCA9 · PDB 5FL65FL6Experimental structureCA9 · PDB 6RQQ6RQQExperimental structureCA9 · PDB 6RQU6RQUExperimental structureCA9 · PDB 8Q198Q19Reaction assignmentCA9 · RHEA:10748 assignmentRHEA:10748