Source assertion

PDBe/SIFTS maps PDB 8Q19 to UniProt Q16790 with chain-level identity and coverage retained.

Evidence ID: STRUCTURE:PDB:8Q19:UNIPROT:Q16790
Subject dossier: ca9
Source chain: uniprot + pdbe
Upstream record: 8Q19
Corpus snapshot: 2026-07-14T09:23:31Z
Admission status: Admitted release record

Experimental structure

The Crystal Structure of Human Carbonic Anhydrase IX in Complex with Sulfonamide

PDB ID: 8Q19
Experimental method: X-ray diffraction
Resolution: %!f(*float64=0xc001fffc80) Å
SIFTS identifier: CAH9_HUMAN
Deposited: 20230731
Released / revised: 20231108 / 20241106

Chain-level mapping

Entity	Chain	Structural asym	Identity	Coverage	UniProt range
1	`A`	`A`	99.0%	60.4%	137–391
1	`B`	`B`	99.0%	60.4%	137–391
1	`C`	`C`	99.0%	60.4%	137–391
1	`D`	`D`	99.0%	60.4%	137–391

Experimental constructs

Entity	Chains / asym IDs	Molecule	Length	Mutation flag	Preparation
1	A, B, C, D / A, B, C, D	Carbonic anhydrase 9polypeptide(L)	257 residues	C41S, N213Q	Genetically manipulated

Interpretation boundary

This record represents an experimentally determined structure, not a predicted model. A co-crystal ligand, if present upstream, does not by itself establish affinity. This record does not infer kinetics, pathway rate, or metabolic flux.

Snapshot provenance

Each retained corpus build input is identified by retrieval time, snapshot path, SHA-256 digest, and exact upstream request. The snapshot files are not embedded in the served binary; the provenance identifiers remain dependencies of this one admitted record, not interchangeable citations.

Retrieved	Snapshot	SHA-256	Upstream request
2026-07-14T09:21:33Z	`raw/uniprot/entries/Q16790.json`	`77abc0523fc4c2b797ea15d860a4bb98365bcf0caec1ee88ba765973570f1f22`	Open exact source
2026-07-14T09:22:01Z	`raw/pdbe/mappings/8q19.json`	`5148eda6df783f4dd42bbce55a5b53a0d38738b519bcfaabe6518b2d45004499`	Open exact source
2026-07-14T09:22:17Z	`raw/pdbe/summary/chunk-04.json`	`9993579d3f578cc0a0be921bfc6aa7a181fb8a074c2cd246c08a1da9b7d92dfc`	Open exact source
2026-07-14T09:22:18Z	`raw/pdbe/experiment/chunk-04.json`	`9fbf526866182ab693088d3c63735d5e62302d743c66532fd0163f0cb378a25b`	Open exact source
2026-07-14T09:22:19Z	`raw/pdbe/molecules/chunk-04.json`	`3e3b75bb7fa19acefd58e3b24f2d7e54feb541eeb253bea88d1e20ba0ccd936c`	Open exact source